Science Strikes Back: Longevity

While longevity and anti-aging innovations impact every sector from financial services to housing, our deep tech investment focus is primarily focused on healthcare and age tech.

Areas of Focus and Benefits

Considering age as a disease that can be treated

• Biological aging really should be considered a disease, often at the core of other diseases, infirmity, and death.
• Many chronic condition and degenerative diseases are at least partially caused by aging: adult onset diabetes, osteoarthritis, Alzheimer’s, cancer, heart disease, etc.
• By addressing these mechanisms, people can age more slowly and significantly postpone or perhaps even prevent age-related diseases and extend healthy, productive years of living.

Slowed-aging

• Developing class of drugs called senolytics.
• Designed to eliminate cells that have ceased to divide and replicate.

Reverse aging

• SENS Foundation and small set of researchers are involved in rejuvenation biotechnology
• Capable of restoring youthful function and vigor

Benefits

• Higher quality of life
• More effective care and treatments
• Lower overall health expenditure costs
• Greater long-term productivity and more financial independence

Innovations in the Wings

• Organs and tissues will be produced from stem cells and 3D bio-printing.
• Nanorobots will be programmed to repair old or diseases cells to bolster immune systems and healing processes.
• Indication expansion—the use of approved and sometimes off-patent, drugs—will increasingly be used for longevity and anti-aging (e.g., acarbose and rapamycin).
• Stem cell therapy will explore pluripotent stem cells that can become any cell in the body, with the potential to be transformed into any young cell or tissue.